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Understanding and mitigating the risks of Pimelea.

With the perfect storm of events this winter, the pimelea growth has skyrocketed. Like the conditions seen in 2021 and 2022, late winter rainfall, followed by cold weather and limited tropical pasture growth has resulted in increased pimelea growth. 



Pimelea is a native plant to Australia and New Zealand, with 150 identified species, of 110 are endemic to Australia. Of the species found around Australia, a small number (4) are associated with poisoning in cattle. 

  • P. elongata
  • P. simplex subsp. continua
  • P. simplex subsp. simplex 
  • P. trichostachya

Figure 1. Pimelea plant species commonly found in QLD, NSW and SA. a) P. simplex subsp. simplex, (b) P. trichostachya and (c) P. elongata (source: Poisonous Plants of the Genus Pimelea: A Menace for the Australian Livestock Industry. Toxins 2023, 15, 374.)

All these plants are considered toxic to cattle and contain the toxic secondary metabolite simplexin. Cattle being the most susceptible to the toxic effects of simplexin, exhibiting distinct symptoms that often lead to long term affects and death in extreme cases. Current suggested management options of livestock include, providing feed supplementation, restricting access to infested pastures and the use of herbicides to reduce spread. Much of this advice is easier said than done, with producers needing to continue to utilise land, feed and input costs already being high and herbicides over large land parcels being too costly. 

Preferred Habitat & Environmental requirements 

As mentioned above, pimelea needs a perfect storm to flourish. All four poisonous species and sub species are annuals and require a specific set of conditions to grow. As a spring flowering plant, they grow well in winter following rainfall and dry summers suppress establishment. The plants abundance depends on the prevailing conditions and can be influenced by the intensity of inter and intra specific competition. Inter- and intra- specific competition refers to the competition for resources between individuals of different species (interspecific) and individuals of the same species (intraspecific). 

Timing of Outbreaks

The conditions that favour outbreaks of poisoning include low summer rain in the previous year 

  • Good autumn and early winter rain
  • Low spring/summer rain with a feed shortage 
  • Land with little perennial pasture either due to:
  • The nature of the land system
  • Insufficient summer rain to support perennial grasses, 
  • Past or present grazing practices.
  • Careful inspection is required following any rain fall of over 20mm in coolers times and 50mm in autumn and spring. 

Poison Action

The toxic component of Pimelea, simplexin, is considered a hydrocarbon fat, similar to fatty acids found widely within the body and other plant materials. Plants naturally synthesis and accumulate secondary metabolites (essential stress response) for a variety of different purposes, often attributed to survival. 



“The does that makes the poison” (Paracelsus 1493-1541), is a phase attributed to many toxic effects of compounds in the world. This phrase also applies to the toxic effects of Pimelea. It is regardless of the plant and/or the toxin’s abundance or distribution, it is the quantity of the intake and absorption that effects the animal. Simplexin toxin is highest in green and growing plants, however due to the smell of the green plant, stock generally avoid it. 

Signs of Pimelea Poisoning 

Pimelea poisoning shows in three types of symptoms

  • Fluid swellings often under the jaw, down the neck, brisket and can extend under the belly
  • Diarrhoea, dark foul smelling and sometimes contains blood 
  • Weight loss
  • Distended jugular veins with prominent pulse 
  • Pale mucus membranes 
  • Breathing difficulties 
  • Reluctance to move 
  • Decreased appetite 
  • Depression 
  • Becoming easily agitated and aggressive 


There are comments from many producers, that certain categories of stock are more susceptible than others. In general, all stock are susceptible to poisoning, dependent on intake irrespective of breed, sex and age. Cattle aged between 18-24 months were most affected as were cows, bulls and heifers. Steers and bullocks seem to be less susceptible, possibly due to producers growing these classes of stock on different country types for improved weight gains. Home bred stock usually avoid areas of high growth, especially when green. This could explain why stock are introduced into pimelea infested areas are more likely to show symptoms when compared to home bred animals. 


Supplementation with sulphur and urea have also ben reported as a tool for decreasing the impact of poisoning. This may be due to the increase protein intake, improving rumen function and increasing rumen passage rate, which may reduce time of absorption in the gut.

Treatment and Prevention 

There is currently no scientifically proven cure for pimelea poisoning. With no immune response triggered and no development of antibodies there is little evidence to suggest an antibiotic, antiviral or vaccine will be a viable treatment and prevention option. 


The QAAFI have been conducting many trials and in vitro research into different techniques for managing and preventing pimelea poisoning. 



A promising trail using different toxin absorbents has led to good results. The most effective binder was sodium bentonite at 12mg/ml, which bound 95% of the simplexin toxin. Both sodium and calcium bentonite remained bound to the toxin for the longest period. 

Reference: Gordon R, Hungerford N, Laycock B, Ouwerkerk D, Fletcher M. 2019. Adsorbents for the sequestration of the Pimelea toxin, simplexin. Poster 352 at the Northern Beef Research Update Conference, Brisbane, 2019 http://www.nabrc.com.au/wp-content/uploads/2019/09/NBRUC-Conference-Proceedings.pdf.

Other research suggests the possibility of using a biodegradable biopolymer as a rumen bolus to continually stimulate to production and proliferation of rumen bacteria that may detoxify the toxin. 


Although the recent wet weather has been welcomed by most, in some areas it has resulted in an unwelcome outbreak of the Toxic Pimelea Plant. 



Ask our friendly staff about our supplement range that can help mitigate the risks associated with Pimelea and reduce its toxicity.


References 

Fletcher, M.; Silcock, R.; Ossedryver, S.; Milson, J.; Chow, S. Understanding Pimelea Poisoning of Cattle. Department of Employment, Economic Development and Innovation, Brisbane, QLD, Australia. 2009. Available online: https://futurebeef.com.au/wp-content/uploads/2011/09/Understanding_pimelea_poisoning_of_cattle.pdf (accessed on 11 April 2023).


Gordon, R. J., Hungerford, N. L., Laycock, B., & Fletcher, M. T. (2020). A review on Pimelea poisoning of livestock. Toxicon, 186, 46-57.


Saleem, R., Bajwa, A. A., Campbell, S., Fletcher, M. T., Kalaipandian, S., & Adkins, S. W. (2023). Poisonous Plants of the Genus Pimelea: A Menace for the Australian Livestock Industry. Toxins, 15(6), 374.


Saleem, R. (2022). Germination triggers, persistence, and management of Pimelea trichostachya Lindl. in Queensland.

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a cow and calf standing in a grassy field
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